Hello.
I am Dr. Bo-hwang Jeong, Director of Cleor Clinic Gangnam.
While looking into double chin injections,
you may have come across the names Pencaira and V-Olet,
and wondered which one is right for you.
Even after searching, you often find repetitive explanations,
leaving the relationship between the two products unclear in many cases.
To start with the conclusion, both products belong to the same essential ingredient family,
and can be seen as options with different release dates and manufacturers in Korea.
Like coffee from different brands made with the same beans,
the core ingredients and mechanism of action are identical,
but the approval timing and manufacturing companies differ.
Today, I will explain what Gangnam Pencaira is,
and walk you through its similarities and differences compared to V-Olet.
What is Gangnam Pencaira?
👉 Gangnam Pencaira is a MFDS-approved specialized double chin lipolysis drug
formulated with Deoxycholic Acid (DCA), a component of human bile acid, as its main ingredient.
Deoxycholic Acid is a type of bile acid originally involved
in breaking down dietary fats within the body.
When this ingredient is purified for medical use and injected directly into the submental subcutaneous fat layer,
it works by irreversibly destroying the membranes of fat cells.
Since it reduces the number of fat cells rather than just their size,
the results are known to be relatively long-lasting.
The destroyed fat cells are naturally excreted from the body over time,
and collagen synthesis is induced in their place,
which is reported to help improve skin elasticity.
Pencaira is produced by Penmix and launched by Juventa Healthcare,
and received MFDS approval in April 2025.
The Relationship Between Pencaira and V-Olet
👉 Both Gangnam Pencaira and V-Olet are MFDS-approved double chin injections
that use the same Deoxycholic Acid ingredient.
Their mechanism of action is identical; they only differ in manufacturer and approval timing.
Overseas, Allergan's Belkyra (known as Kybella in the US)
was the first well-known DCA double chin injection.
In Korea, since Belkyra's market withdrawal in 2020,
Korean-made products with the same Deoxycholic Acid ingredient have been approved by the MFDS and are in use.
Because the core ingredients, mechanism of action, and indications are the same,
rather than concluding that "one is more effective,"
it is more accurate to understand them as options within the same category.
V-Olet was the first to establish itself in the Korean market,
and Pencaira can be seen as a subsequent option within the same ingredient family.
Effects and Advantages of Gangnam Pencaira
👉 The key advantages of Gangnam Pencaira can be summarized into three points:
non-surgical approach, reduction in the number of fat cells, and accompanying collagen synthesis.
First, it is a non-surgical method performed without incisions.
Since it is performed via injection without the burden of surgery like liposuction,
the recovery burden is reported to be relatively low.
Second, it reduces the number of fat cells, not just their size.
While standard contouring injections focus on shrinking the volume of fat cells,
DCA injections destroy cell membranes so that cells are excreted from the body,
which is known to provide relatively long-lasting results.
Finally, it induces collagen synthesis.
As collagen is synthesized where fat has been reduced,
it is reported to help tighten skin sagging.
Who is Gangnam Pencaira Recommended For?
Those whose submental fat remains despite dieting
Those who did not see sufficient results from standard contouring injections
Those who want a structural approach to their double chin without surgery
Those looking into DCA-based treatments like V-Olet and wanting to compare options
Those who want long-lasting results
⚠️ Precautions Before and After Gangnam Pencaira Treatment
👉 Gangnam Pencaira is a procedure where results stabilize when specific precautions are followed both before and after the treatment.
Side Effects and Important Considerations for Gangnam Pencaira
👉 Rather than being completed in a single session,
Gangnam Pencaira results stabilize when 2–3 sessions are performed at intervals of 4 weeks or more.
During the process where the DCA ingredient destroys fat cell membranes,
a localized inflammatory response is a natural occurrence.
This response leads to post-treatment swelling,
which is reported to subside within 1–2 weeks in most cases.
However, depending on individual reactions, swelling may last longer than 2 weeks.
In addition to swelling, bruising, temporary pain, or a tingling sensation at the injection site
may occur for a few days, and the degree of reaction varies
depending on the practitioner's concentration and dosage design.
Please inform us in advance as treatment may be restricted in the following cases:
If you are pregnant or breastfeeding
If there is an active infection, inflammation, or wound at the treatment site
If you have a history of allergies to DCA or related ingredients
If you are taking medications that increase the risk of bleeding
If you are being treated for autoimmune diseases or thyroid abnormalities
❓ Frequently Asked Questions (FAQ)
Q. Is there a difference in effectiveness between Gangnam Pencaira and V-Olet?
Since the core ingredients and mechanism of action are identical,
the essential effects can be considered within the same category.
However, differences in perceived results may occur
depending on the concentration/dosage design and the practitioner's technique.
Q. How many sessions of Gangnam Pencaira are required?
It varies depending on the amount of fat and individual condition,
but it is common to perform 2–3 cumulative sessions at intervals of 4 weeks or more.
It is safer to check the results after the first session before deciding on additional treatments.
Q. What happens if I gain weight again after receiving Gangnam Pencaira?
Since DCA injections work by reducing the number of fat cells,
the results are known to be relatively long-lasting.
However, in cases of extreme weight gain or hormonal changes,
remaining fat cells may enlarge, making the area prominent again.
Q. Is severe swelling normal after Gangnam Pencaira?
During the process where the DCA ingredient destroys fat cell membranes,
it is a natural reaction for swelling to accompany the localized inflammatory response.
It usually subsides within 1–2 weeks, but if it persists for more than 2 weeks,
it is recommended to have your condition checked during a follow-up consultation.
Q. Can Gangnam Pencaira be used on areas other than the double chin?
The MFDS-approved indication is for submental (under-the-chin) fat.
While overseas studies report cases of application to other areas,
it differs from the official indications in Korea,
so it is best to confirm this directly during a consultation.
Q. Should I choose Gangnam Pencaira or V-Olet?
Since they are essentially the same ingredient family,
it is difficult to conclude that "one is better than the other."
The suitable option varies based on the practitioner's preferred dosage design and your condition,
so it is best to decide together during a consultation.
The double chin is an area that is difficult to manage with exercise or diet,
so non-surgical injection options have been consistently utilized.
Gangnam Pencaira, along with V-Olet from the same Deoxycholic Acid family,
is an MFDS-approved option focused on reducing the actual number of fat cells.
The treatment direction and number of sessions suitable for your chin condition
will be determined during your consultation.
If you are concerned about submental fat that does not go away with dieting,
please feel free to visit Cleor Clinic Gangnam.
Even before deciding on a procedure, we will examine your fat volume and distribution through a consultation
and provide detailed guidance on the most suitable care plan.
※ This content is for general informational purposes, and results may vary by individual.
Please consult with a specialist for an accurate diagnosis and to determine treatment suitability.
▼ Cleor Double Chin Injection Pencaira ▼
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