If you are curious about the eye rejuvenation ingredients extracted from salmon DNA used in Rejuran I at our Gangnam branch

September 18, 2026

Hello.

I am Dr. Jung-Hwang Information, Director of Cleor Clinic Gangnam Branch.

Have you ever searched for Rejuran after hearing it is effective, only to become intrigued by the description that it is derived from salmon DNA?

"I looked it up because I was curious about how Rejuran differs from other skin boosters, and I found out it is made from DNA extracted from salmon.

I want to know how this ingredient actually works on the skin,

and if it is applied in a special way for the eye area."

This is a question many people actually have.

The PN ingredient in Rejuran is a biopolymer similar to the DNA composition of our bodies, so

the way it reacts with cells is completely different from other skin boosters.

While general hyaluronic acid skin boosters focus on hydration,

Rejuran is known to work by inducing the regeneration of the skin tissue itself, making the approach fundamentally different.

The option that uses this ingredient in a formulation specifically for the eye area is Gangnam Rejuran i.

Today, I will summarize how the PN ingredient in Rejuran was developed,

what kind of reactions it triggers at the cellular level,

and why a separate formulation is necessary for the eye area.

What is Gangnam Rejuran i?

👉 Gangnam Rejuran i is a skin booster specifically for the eye area, formulated with PN (polynucleotide) extracted from salmon testes to suit the thin and sensitive skin around the eyes. It is an option that approaches fine lines and dark circles by inducing the regeneration of the dermal tissue itself.

Rejuran is a PN-based skin booster brand developed by PharmaResearch in Korea.

While general hyaluronic acid skin boosters provide hydration,

Rejuran is known to work by sending regenerative signals to skin cells to restore the tissue itself.

This approach is particularly suitable for the thin and sensitive eye area, but

even with the same ingredient, the formulation used for other parts of the face can be too heavy for the eye area.

To reduce this burden, the concentration and formulation were adjusted specifically for the eyes, which is the Rejuran i option,

and at our Gangnam branch, we offer the 1cc Rejuran i option.

What is the PN (polynucleotide) ingredient?

👉 The core ingredient of Gangnam Rejuran i, PN, is a polymer substance derived from biological tissue,

and it works by binding to cell surface receptors to activate regenerative signals.

The identity of PN

PN (Polynucleotide) is a biopolymer in which nucleotides are linked in a chain form.

Since our body's DNA and RNA are also composed of nucleotides,

it is known to have very high biocompatibility.

Thanks to this characteristic, it has a low rate of foreign body reactions even when injected externally,

  • and it is reported that higher levels of purification ensure greater safety.

Why is it extracted from salmon?

Rejuran is produced by purifying PN from the testes of salmon and trout.

Salmon testes were chosen because they have a high PN content and are structurally similar to human DNA,

which is known to result in good cellular reactivity.

The extracted PN goes through several stages of advanced purification,

removing allergy-inducing proteins and leaving only the active ingredients.

Cellular mechanism of action

When PN is injected into the dermis, it binds to receptors on the cell surface and activates regenerative signals.

Once these signals are turned on, the following reactions occur sequentially.

Clinical studies have confirmed that this leads to the activation of cellular self-regeneration, promotion of collagen and elastin synthesis,

induction of anti-inflammatory effects, and support for new blood vessel formation.

  • Because of this process, it is known that the results settle in a way that the tissue itself is restored.

Why a separate formulation is needed for the eye area

👉 Gangnam Rejuran i is an eye-specific option with re-adjusted concentration and ingredient ratios to suit the eye area, which has completely different tissue characteristics from other parts of the face.

Tissue characteristics of the eye area

The skin around the eyes is known to be thinner and have a much shallower fat layer compared to other parts of the face.

Blood vessels and nerves are distributed close to the surface, making it sensitive to irritation,

and it has fewer sebaceous glands, making it difficult to form its own moisture barrier.

Difference from general Rejuran

  • General formulations like Rejuran Healer are designed for the entire face,

so the concentration is reported to be potentially burdensome for the eye area.

Although Rejuran i uses the same PN ingredient, the concentration is re-adjusted to suit the eyes,

and the ingredient characteristics are adjusted so that it can be precisely placed in the thin dermal layer.

  • Fundamental approach to dark circles and fine lines

Since eye dark circles are often caused by a complex combination of pigmentary, vascular, and structural factors,

it is known that they are often difficult to solve with a single approach.

Rejuran i approaches this by inducing dermal tissue regeneration to restore skin thickness

and reducing the visibility of blood vessels.

  • Fine lines often start from damage to the dermis rather than the epidermis,

and it is known that PN induces collagen synthesis in the dermis to provide a fundamental improvement.

Effects and advantages of Gangnam Rejuran i

👉 Gangnam Rejuran i is an approach that combines three strengths into one option: eye tissue regeneration, addressing fine lines and dark circles, and low irritation.

Regeneration of eye tissue itself

PN activates cell regeneration signals to restore the thinned dermis around the eyes.

It is reported that the results are natural because it is not a method of filling with foreign substances,

but rather regeneration produced by your own tissue.

Simultaneous management of fine lines and dark circles

  • As collagen and elastin synthesis is induced, fine lines are reduced,

and the restoration of dermal thickness reduces the visibility of blood vessels,

leading to an improvement in dark circles.

The ability to address both concerns with one option is known to be a strength.

  • Low irritation burden

Since Rejuran i is a formulation specifically for the eye area, it has a lower irritation burden than Rejuran for the entire face.

It is reported to be suitable even for those who are new to eye care because the burden on the sensitive eye area is low.

Who is Gangnam Rejuran i suitable for?

Those who are curious about and researching Rejuran ingredients and effects

  • Those who want to manage eye fine lines and dark circles together

Those who feel that eye cream is not enough for fundamental improvement

Those whose skin under the eyes is thin, making blood vessels visible

Those who want low-irritation eye care

  • Those who are concerned about the deterioration of eye condition after their 30s

  • Side effects and things to know in advance about Gangnam Rejuran i

  • 👉 Although Gangnam Rejuran i is an option that utilizes the highly biocompatible PN ingredient,

  • because it is a procedure on the sensitive eye area, the practitioner's precise technique and individual skin reactions can affect the results.

  • Immediately after the procedure, redness, minor swelling, and thin bruising may occur at the injection site.

  • Generally, these resolve naturally within a few days,

but since the eye area is a region with dense blood vessels, there is a possibility of minor bruising, so

it is necessary to adjust your schedule if you have important events coming up.

Rejuran i is performed using a manual injection method,

so the practitioner's accurate judgment and technique are particularly important.

Because the results settle stably only when distributed evenly in the correct layer of the eye area,

the procedure direction is decided after checking your eye condition during a pre-procedure consultation guided by experienced medical staff.

Although PN is a salmon-derived ingredient, it is highly purified,

so it is reported that allergy-causing proteins have been removed.

However, if you have a severe seafood allergy, please be sure to inform us during the pre-procedure consultation.

Since the results of the procedure accumulate over several sessions, it is known that

rather than a dramatic change after one session, stable improvement is confirmed with regular sessions.

If any of the following apply to you, the procedure may be restricted or

may require prior confirmation, so please inform us during the consultation.

If you are pregnant or breastfeeding

If you have active infections, wounds, or herpes at the injection site

If you have a history of salmon or seafood allergies

If you are regularly taking anticoagulants or antiplatelet agents, or have a bleeding tendency

If you have been diagnosed with an autoimmune disease or keloid tendency

If you have a history of filler or thread procedures in the eye area recently

  • If you have a history of allergies to specific ingredients

  • ⚠️ Precautions before and after Gangnam Rejuran i procedure

  • 👉 Gangnam Rejuran i is an option where result stability and recovery speed depend on pre-procedure condition management and post-procedure UV and moisture care.

  • ❓ Frequently Asked Questions (FAQ)

  • Q. When can I see the results of Gangnam Rejuran i?

  • Improvement in eye condition is generally confirmed gradually starting 2-3 weeks after the procedure.

  • It is known that improvements in fine lines, skin thickness, and dark circles accumulate with regular sessions of 3 or more,

and due to the regenerative induction characteristics of the PN ingredient, the results become more distinct as the number of sessions increases.

Q. Is Gangnam Rejuran i effective for dark circles?

It is an approach that addresses vascular and structural dark circles rather than pigmentary ones.

It is known that as the skin thickness under the eyes is restored through dermal tissue regeneration,

the visibility of blood vessels is reduced, leading to an improvement in dark circles.

For dark circles caused by pigmentation, combinations with other care are considered.

Q. How is Gangnam Rejuran i different from general Rejuran?

The basic ingredient, PN, is the same, but the formulation is different.

While general Rejuran (Rejuran Healer) is designed for the entire face,

Rejuran i is an eye-specific option with a re-adjusted concentration to suit the thin and sensitive eye area, so it is reported to have a lower irritation burden.

Q. How much pain is involved in the Gangnam Rejuran i procedure?

It is performed after applying numbing cream before the procedure, and strong pain is low.

It is injected using a manual injection method with a thin needle at multiple points in small amounts,

and it is known to be at a tolerable level despite some irritation during the procedure.

Q. How many sessions of Gangnam Rejuran i should I receive?

Generally, regular sessions of 3 or more at 2-4 week intervals are recommended.

Accumulating sessions is more important for satisfaction than a single procedure,

and it is known that continuing with maintenance care afterward is suitable.

Q. Can I combine Gangnam Rejuran i with other eye procedures?

Yes, it is possible.

Since Rejuran i is specialized for tissue regeneration, combinations with other procedures are considered for eye areas that need volume restoration or lifting.

The procedure order and intervals will be guided in a suitable direction during the pre-procedure consultation.

Q. When can I wear makeup after the Gangnam Rejuran i procedure?

Gentle eye makeup is generally possible from the evening of the procedure day.

It is better for recovery stability to refrain from using cosmetics that cause strong irritation to the eye area or

heavy eye makeup for a few days.

Rejuran is a skin booster brand that utilizes PN ingredients purified from salmon testes to

induce the regeneration of the skin tissue itself.

While general hyaluronic acid skin boosters focus on hydration,

the fundamental difference is known to be that Rejuran works by activating cell regeneration signals to restore the dermal tissue.

The option that uses this ingredient in a formulation suitable for the thin and sensitive eye area is Gangnam Rejuran i.

At our Gangnam branch, we operate various Rejuran series options in addition to Rejuran i.

Rejuran Healer 2cc for elasticity and fine line management,

Rejuran HB Plus 1cc, a premium option with reduced pain burden,

and even Lipjuran (lip Rejuran) for lip hydration and dryness improvement,

you can choose the Rejuran option that suits your management area and purpose.

We will personally check the direction that fits your eye condition and management goals during the consultation.

If you want to manage your eye area from the root with PN ingredients purified from salmon DNA,

please feel free to visit Cleor Clinic Gangnam Branch.

Even before deciding on the procedure, you can check your eye condition and a suitable session plan together through a pre-procedure consultation.

※ This content is for general information purposes only, and results may vary by individual.

Please decide on the exact diagnosis and procedure through a consultation with a specialist.

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연어 DNA에서 정제된 PN 성분으로 눈가를 근본부터 관리하고 싶으시다면

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