Hello.
I am Dr. Information, Director of Cleor Clinic Gangnam Branch.
Have you ever experienced acne that keeps coming back in the same spot, or a face that has become so sensitive and red that it won't calm down, even after trying acne medication and switching to various trouble-care products?
"I've tried many different skincare products for my breakouts, but my face seems to have become even more sensitive.
I'm looking for a fundamental treatment that can strengthen the skin itself, and I'm curious about the principle behind how exosomes manage skin troubles."
I frequently hear these questions in my consultation room.
In many cases, recurring skin troubles are difficult to resolve with surface-level care alone.
This is because when the condition of the skin cells themselves has collapsed—due to factors like damaged skin barriers, decreased dermal collagen, and unstable immune balance—simply managing the visible breakouts will inevitably lead to them recurring.
The approach that restores this cellular condition is the Gangnam D-Hive Exosome.
Today, I will explain the principles of how exosomes work on the skin, the differences between D-Hive Exosome and the original ASCE Exosome, and which skin conditions they are suitable for.
What is Gangnam D-Hive Exosome?
👉 Gangnam D-Hive Exosome is a 4th-generation skin booster treatment that involves injecting exosomes—nano-vesicles isolated from stem cell culture media—directly into the dermis to activate intercellular signaling and induce the skin's own regeneration and recovery. It is a line specifically specialized for managing breakouts and inflammation.
Exosomes are nano-sized vesicles naturally secreted by cells.
As substances that play a role in intercellular information transfer, they act as key mediators that deliver regeneration and recovery signals to skin cells.
While existing skin boosters involve injecting a single specific ingredient (such as PN, PDLLA, or HA),
exosomes are a comprehensive signaling delivery system containing over 300 types of growth factors, proteins, and nucleic acids, making the principle of inducing skin cell activation and environmental improvement different.
At our Gangnam branch, we offer two lines: D-Hive Exosome, specialized for calming breakouts, and the original ASCE Exosome, specialized for comprehensive regeneration and anti-aging,
allowing you to choose according to your skin condition and treatment goals.
How exosomes work on troubled skin
👉 Exosomes approach troubled skin fundamentally through four stages: activating cell signaling, inducing anti-inflammatory responses, restoring the skin barrier, and preventing recurring breakouts.
Activating cell signaling
When injected exosomes meet skin cells,
growth factors, proteins, and nucleic acids are delivered into the cells.
As these signals transmit commands for regeneration and recovery to the cells,
the skin cells themselves are activated.
Inducing anti-inflammatory responses
The anti-inflammatory ingredients and signals contained in the exosomes
regulate the inflammatory response in the trouble-prone areas.
Inflammatory skin reactions such as acne, redness, and atopy are alleviated,
and the skin settles into a state where redness and heat are calmed.
Restoring the skin barrier
Through cell activation and signal transmission,
the thinned and damaged skin barrier is restored from within.
As the skin's defense against external stimuli is strengthened,
the sensitive skin condition stabilizes.
Preventing recurring breakouts
As the condition of the skin cells themselves is restored,
the root cause of recurring breakouts is managed.
Rather than just temporary soothing, the skin environment is improved in the long term,
alleviating the cycle of acne that repeats in the same spot.
Differences between D-Hive Exosome and the original ASCE Exosome
👉 At our Gangnam branch, we operate two lines: D-Hive Exosome, specialized for calming breakouts, and the original ASCE Exosome, specialized for comprehensive regeneration and anti-aging. The choice depends on your skin condition and treatment goals.
D-Hive Exosome - Specialized for breakouts
D-Hive Exosome is an option focused on calming breakouts and inflammation.
Designed with a prescription focused on anti-inflammatory and antioxidant effects,
it is suitable for managing active acne, recurring breakouts, redness, and sensitive skin conditions.
As it is an option that is easy to approach without burden,
it is frequently chosen by those who continue regular breakout management.
Original ASCE Exosome - Comprehensive regeneration and anti-aging
The original ASCE Exosome is a representative line of verified 4th-generation skin boosters.
It contains 5 billion high-purity exosome particles isolated from stem cell culture media,
along with 5 types of growth factors, 6 types of peptides, 19 types of amino acids, 4 types of coenzymes, and even vitamins, minerals, and glutathione.
It minimizes the loss of active ingredients in a freeze-dried powder form,
and as a verified option with US patents,
it is suitable for those who want comprehensive anti-aging—including elasticity, wrinkles, skin tone, and texture—in addition to breakout management.
Selection criteria
If managing active acne and recurring breakouts is the priority, D-Hive Exosome is recommended.
If you need comprehensive skin regeneration and anti-aging along with breakout management,
the original ASCE Exosome is suitable.
Since both options aim to activate the cells themselves,
we also consider combinations where they are alternated regularly according to need.
Why exosomes are different from existing skin boosters
👉 Unlike existing skin boosters that inject a single specific ingredient, exosomes are 4th-generation skin boosters that deliver a comprehensive signaling system containing over 300 types of growth factors, proteins, and nucleic acids to induce the activation of the cells themselves.
Difference from Rejuran
Rejuran is a method that delivers a single ingredient, Polynucleotide (PN) extracted from salmon, into the dermis to induce DNA recovery, barrier strengthening, and moisture improvement.
Exosomes deliver a comprehensive signaling system rather than a single ingredient,
inducing the activation and regenerative capacity of the skin cells themselves.
Difference from Juvelook
Juvelook is a collagen booster that uses PDLLA (poly-D,L-lactic acid) and hyaluronic acid
to induce both collagen regeneration and volume recovery.
Exosomes do not fill in ingredients or stimulate collagen directly,
but rather deliver regeneration commands through intercellular signals, so the approach is different.
Possibility of combination
Since the three treatments have different principles, they can be combined.
Combinations such as restoring dermal condition with Rejuran or Juvelook while activating the cells themselves with exosomes are frequently considered.
Gangnam D-Hive Exosome lineup
👉 At our Gangnam branch, we operate two lines: D-Hive 5cc for breakout specialization and original ASCE 5cc for comprehensive regeneration, which you can choose according to your skin condition and treatment goals.
Generally, stable results are established after 3–5 sessions at 3–4 week intervals,
and regular care leads to continuous improvement in skin condition.
We will examine the option that suits your skin condition and treatment goals during the pre-treatment consultation.
Who is a good candidate for exosomes?
Those who have acne that repeatedly appears in the same spot
Those who have persistent redness or sensitive skin conditions
Those who feel their skin barrier has thinned and are sensitive to stimuli
Those who have not felt significant changes even with trouble-care skincare products
Those who want to fundamentally restore their skin condition from the root
Those who want to use it as a recovery and regeneration booster after other procedures
Side effects of Gangnam D-Hive Exosome and things to know in advance
👉 Although Gangnam D-Hive Exosome is a procedure performed based on verified clinical data,
reactions may vary depending on individual skin conditions and allergy history.
Immediately after the procedure, you may experience mild redness, slight swelling, thin bruising,
or temporary heat in the treated area.
These generally resolve naturally within a few days.
Exosomes are characterized by gradual improvement through cell activation rather than immediate volume changes.
You will begin to feel improvements in your skin condition a few days after the procedure,
and the results will become more stable as the number of sessions increases.
Rather than expecting fundamental improvement from a single session,
it is better for result stability to proceed with 3–5 sessions.
We recommend waiting one week after the procedure before using irritating home care (scrubs, strong acidic products),
and the use of sunscreen is very important for stable recovery.
Following the guidance of our experienced medical staff, the suitable option will be decided after checking your skin condition and breakout status during the pre-treatment consultation.
If any of the following apply to you, please inform us during the consultation as the procedure may be restricted or require prior confirmation.
If you are pregnant or breastfeeding
If there is an active infection or severe inflammation in the treatment area
If you have been diagnosed with an autoimmune disease
If you are regularly taking anticoagulants or antiplatelet agents, or have a bleeding tendency
If you have recently undergone a strong peeling or laser procedure
If you have a history of allergies
⚠️ Precautions before and after exosome treatment
👉 Exosome treatment is a procedure where result stability depends on pre-treatment condition management and post-treatment home care.
❓ Frequently Asked Questions (FAQ)
Q. When can I see the results of Gangnam D-Hive Exosome?
You will begin to feel improvements in your skin condition a few days after the procedure.
The full cellular regeneration response settles in over time after the procedure,
and stable results are confirmed when proceeding with 3–5 sessions.
Q. Should I choose D-Hive or the original ASCE?
It depends on your treatment goals.
If managing active acne and recurring breakouts is the priority, D-Hive Exosome is recommended; if you want comprehensive skin regeneration and anti-aging in addition to breakout management, the original ASCE Exosome is suitable.
Q. How many sessions should I receive?
Generally, stable results are established after 3–5 sessions.
When received regularly at 3–4 week intervals, cellular regeneration responses accumulate,
and skin condition improves continuously.
Q. How painful is the procedure?
It is performed after applying an anesthetic cream, so there is no significant pain.
Since it is a method of injecting small amounts into multiple points with a thin needle,
the burden is relatively low, and any soreness after the procedure resolves naturally.
Q. Can it be combined with other skin boosters?
Yes, it can be combined.
When performed together with options that restore dermal condition, such as Rejuran or Juvelook,
it is a frequently considered combination as it allows for both cell signaling and dermal regeneration.
Q. Is there any downtime?
Redness and slight swelling resolve within a day after the procedure, and there is no interference with daily life the next day.
Light makeup is possible from the evening of the procedure, and you only need to ensure you use sunscreen.
Q. Does it improve acne scars?
Deep acne scars are difficult to improve with exosomes alone,
and combination with dermal stimulation procedures like Potenza or Fraxel is necessary.
Shallow scars and acne pigmentation are alleviated through the course of exosome sessions.
Q. Can I wear makeup after the procedure?
Normal makeup is possible from the day after the procedure.
On the day of the procedure, avoid irritation and only use sunscreen, and it is best to use mild products for a few days after the procedure for stable recovery.
Recurring breakouts and sensitive skin are signals that the condition of the skin cells themselves has collapsed.
Surface care alone is difficult to reach the root cause,
which is why an approach that restores skin cells and signaling itself is necessary.
Gangnam D-Hive Exosome is a 4th-generation skin booster that injects exosomes—nano-vesicles isolated from stem cell culture media—directly into the dermis to activate intercellular signaling and induce the skin's own regeneration and recovery, and it is a line specifically specialized for calming breakouts and inflammation.
At our Gangnam branch, we have two lines prepared: D-Hive Exosome, specialized for calming breakouts, and the original ASCE Exosome, specialized for comprehensive regeneration and anti-aging.
D-Hive Exosome is suitable for those who want to approach active acne, recurring breakouts, redness, or sensitive skin conditions without burden,
and the original ASCE Exosome is suitable for those who want elasticity, wrinkles, and tone improvement in addition to breakout management through comprehensive active ingredients such as 5 types of growth factors, 6 types of peptides, and 19 types of amino acids.
Although they are both exosome treatments, you can choose between the two lines according to your goals,
allowing you to approach the treatment according to your skin condition and management plan.
We will personally check the direction that suits your skin condition and treatment goals during the consultation.
If you want to manage recurring breakouts and sensitive skin from the root,
please feel free to visit Cleor Clinic Gangnam Branch.
Even before deciding on a procedure, you can examine your current skin condition through a pre-treatment consultation.
※ This content is for general information purposes only, and results may vary by individual.
Please decide on accurate diagnosis and treatment through consultation with a specialist.
▼ Cleor Exosome ▼
https://gangnam.cleorclinic.com/ko/treatments/피부/스킨부스터/엑소좀
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Q. 시술 후 화장이 가능한가요?
시술 다음 날부터 정상적인 메이크업이 가능합니다.
시술 당일은 자극을 피하고 자외선 차단제만 챙기시고,
시술 후 며칠간은 순한 제품으로 관리하시는 것이 회복 안정에 좋습니다.
반복되는 트러블과 예민해진 피부는
피부 세포 자체의 컨디션이 무너진 상태에서 나타나는 신호입니다.
표면 케어만으로는 근본 원인에 접근이 어려워
피부 세포와 신호 전달 자체를 회복시키는 접근이 필요한 이유입니다.
강남 디하이브 엑소좀은 줄기세포 배양액에서 분리한 나노 소포체 엑소좀을 진피에 직접 주입해
세포 간 신호 전달을 활성화하고 피부 스스로 재생과 회복을 유도하는 4세대 스킨부스터이며,
특히 트러블과 염증 진정에 특화된 라인입니다.
강남점에서는 트러블 진정 특화의 디하이브 엑소좀과
종합 재생·안티에이징 특화의 오리지널 ASCE 엑소좀 두 라인이 준비되어 있어요.
디하이브 엑소좀은 활동성 여드름과 반복 트러블,
홍조나 예민한 피부 상태에 부담 없이 접근하고 싶으신 분들에게 어울리고,
오리지널 ASCE 엑소좀은 5종 성장인자, 6종 펩타이드, 19종 아미노산 같은
종합 활성 성분으로 트러블 관리에 더해 탄력·주름·톤까지 함께 원하시는 분들에게 어울립니다.
같은 엑소좀 시술이지만 목적에 맞춰 두 라인을 선택하실 수 있어
본인 피부 상태와 관리 계획에 맞춰 접근할 수 있습니다.
본인 피부 상태와 관리 목적에 맞는 방향은 상담 시 직접 확인해 드립니다.
반복되는 트러블과 예민해진 피부를 근본부터 관리하고 싶으시다면
클레오르의원 강남점으로 부담 없이 방문해 주세요.
시술 결정 전이라도 사전 진료를 통해
본인 피부의 지금 상태를 함께 살펴보실 수 있습니다.
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정확한 진단과 시술 여부는 전문의 상담을 통해 결정하시기 바랍니다.
▼ 클레오르 엑소좀 ▼
https://gangnam.cleorclinic.com/ko/treatments/피부/스킨부스터/엑소좀
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