A Comprehensive Comparison of Gangnam Skin Boosters: Rejuran vs. Exosomes vs. Juvelook

March 18, 2026

Hello.

This is Dr. Hwangkang Bo, head physician at Cleor Clinic Gangnam.

"I've heard all three are good for skin regeneration, but

honestly, I don't know what the difference is."

"I went to get Exosome injections because they're trendy,

but there's also Rejuran and Juvelook... which one is good for me?"

Rejuran, Exosome, and Juvelook are all treatments aimed at improving the skin,

but the principles they operate on, the timing of their effects,

and the suitable skin types are all different.

It's known as a famous skin booster,

so many people mistakenly think they are similar treatments,

but in reality, there are quite a few differences in ingredients and approach.

Today, we will break down the pros and cons of each treatment for those who are curious about

how the three treatments differ and

which treatment is better suited for whom.

Noticeable skin changes, why do they occur?

Skin aging is not just about wrinkles.

Collagen and elastic fibers in the deep layers of the skin decrease,

and the rate of cell regeneration slows down, resulting in a decline in overall skin texture and elasticity.

The following changes typically occur:

  • Rough skin texture and enlarged pores

  • Decreased elasticity and a feeling of sagging contours

  • Thinning skin and loss of vitality

  • Increased fine lines and dull skin tone

To fundamentally improve these changes,

skin regeneration treatments such as Rejuran, Exosome, and Juvelook have emerged.

What are the principles of each of the three treatments?

  • Rejuran Healer

Rejuran Healer is a treatment that directly injects PDRN (Polydeoxyribonucleotide) extracted from salmon

into the skin.

PDRN induces the regeneration of damaged cells and

plays a role in alleviating inflammation,

In simple terms, you can understand it as a method of

creating an environment where skin cells can recover on their own.

It focuses on restoring skin tissue damaged by aging, UV rays, or external stimuli,

and is particularly suitable for sensitive or damaged skin.

Exosome

  • Exosomes are nano-sized substances secreted by stem cells,

which play a role in transmitting signals between cells.

Because it works by sending regeneration and recovery signals to surrounding skin cells,

the regeneration speed is fast, and

skin radiance improvement after the procedure tends to appear relatively quickly.

Recently, it has also been used in conjunction with other procedures such as lasers or peels

to help skin recover.

Juvelook

  • Juvelook contains PDLLA (Poly-D,L-lactic acid) which

gradually decomposes in the skin,

continuously stimulating collagen production.

Rather than immediate changes,

it is a treatment that improves the skin structure itself over time,

and has strengths in improving elasticity and fine lines.

With a product composition that includes hyaluronic acid complex,

you can expect some level of hydration even immediately after the procedure.

How does the procedure progress?

All three procedures involve injecting

the active ingredient directly into the skin through micro-injections.

It is relatively less burdensome in that it does not require major incisions or anesthesia and allows you to

maintain your daily life.

It usually proceeds in the following order:

Checking skin condition and establishing a treatment plan

  • Applying numbing cream (approximately 20-30 minutes)

  • Injecting the active ingredient into the treatment area (approximately 20-40 minutes)

  • Soothing care and cooling

  • Providing aftercare instructions and returning home

  • However, downtime varies from procedure to procedure.

Exosome has a shorter recovery period among the three, and

Juvelook may cause papules or swelling after the procedure that

may last for a relatively long time, so it is best to

consult with sufficient time before important events.

Recommended for these people

The appropriate treatment may vary depending on the type of skin concern.

When Rejuran Healer is suitable

  1. : Recommended for those with sensitive skin or a lot of damage from external stimuli,

those whose main goal is to improve pores and skin texture,

and those who want consistent skin care.

When Exosome is suitable

  1. : Suitable for those who want rapid skin regeneration and radiance improvement,

those who want to use it in conjunction with other procedures such as lasers or peels,

and those who want to improve dull and tired-looking skin tone.

When Juvelook is suitable

  1. Recommended for those whose main concerns are loss of elasticity and fine lines,

those who want the effect to last a long time,

and those who want to improve skin thickness and volume together.

Of course, there are cases where two treatments are combined.

For example,

first capturing rapid regeneration and radiance with Exosome,and managing long-term elasticity improvement together with Juvelook

is an example of that.However, it is important to determine which combination is appropriate after

directly checking the skin condition.

Things to know before the procedureSince all three procedures are direct injection methods, the treatment plan is important.

The following are common precautions to take after the procedure:

Avoid alcohol, strenuous exercise, and saunas on the day of the procedure.

  • It is best not to press or irritate the treated area with your hands.

  • Use sunscreen thoroughly and avoid strong sun exposure.

  • Maintaining sufficient skin hydration will help with recovery.

  • If you are pregnant or breastfeeding, be sure to consult with a healthcare provider in advance before deciding.

  • Frequently Asked Questions (FAQ)

Q. Which of the three treatments is the best?

It is difficult to say which one is absolutely superior.

This is because the appropriate treatment varies depending on the skin condition and goals.

It is important to first identify what your skin concerns are

rather than simply following trends.

Q. How many treatments do I need to receive to see results?

Rejuran Healer is usually recommended as a basic course of 4 treatments at 4-week intervals,

and Juvelook is guided based on 3-4 treatments at 2-4 week intervals.

The number of Exosome treatments may vary depending on the purpose and skin condition.

Q. Is it possible to return to daily life immediately after the procedure?

In most cases, daily life is possible,

but swelling or papules may appear depending on the individual,

so it is best to schedule the procedure with plenty of time before important events.

Q. Can I receive multiple treatments at once?

Combination treatments are possible depending on the skin condition,

but if multiple treatments are performed at once,

the irritation to the skin may increase.

It is recommended to establish a plan step by step through consultation.

Rejuran, Exosome, and Juvelook each work on the skin

with different principles.

Even if you have the same goal, the results may vary depending on which route youtake, so the process of accurately identifying your skin condition is the first step before choosing a treatment.

If you are considering skin regeneration treatment, it is helpful to

consult with a healthcare provider before making a decision rather than deciding alone.

If you need more detailed consultation, we will guide you at Cleor Clinic Gangnam. ^^

피부재생 시술을 고민 중이시라면 혼자 결정하기보다

의료진과 충분히 상담을 거친 뒤 방향을 정하시는 것이 도움이 됩니다.

보다 자세한 상담이 필요하시다면 클레오르의원 강남점에서 안내해 드리겠습니다 ^^