
Hello.
This is Director Hwang Jeong-hwang of Cleor Clinic Gangnam Branch.
Have you ever stood in front of a mirror for a long time because you could feel a lump on one side weeks after getting filler, or because the left and right sides looked slightly different?
Even after being told it would become natural over time, do you find yourself constantly touching that spot?
Hyaluronic acid filler remains in the shape of the amount and location where it was injected.
Therefore, if the placement is slightly off or the amount is excessive, that state persists throughout the duration of the filler.
However, there is one way to reverse this material.
This is because there is an enzyme that cuts the same chains.
Today, I will explain in order what kind of enzyme is used for Gangnam filler side effect Hyalase, how its approved efficacy differs from its actual use, and what you must check before receiving it.
What is Gangnam filler side effect Hyalase?
👉 Hyalase is a procedure that uses an enzyme that cuts hyaluronic acid chains into small pieces to break down hyaluronic acid filler.
The product used at Cleor Clinic Gangnam Branch is 1cc of high-purity liquid Hyalase (Hyalax).

The domestic approved efficacy of this enzyme is to assist in the dispersion and absorption of drugs.
Because it has the property of cutting hyaluronic acid into small pieces, that property is used to dissolve filler.
As it is a high-purity liquid formulation, it is easier to maintain a consistent concentration than the method of dissolving powder, and it is easier to adjust the amount according to the required area.
However, there is something you should know. Reversibility is limited to hyaluronic acid-based fillers.
Since this enzyme only acts to break down hyaluronic acid, it does not affect injectables made of other materials such as fat or calcium.
Therefore, the very first step before proceeding is to check what was injected.
This is because it must be clear where, what material, and when it was injected to determine if it is an area that can be treated with this enzyme.
Mechanism of Action
👉 The enzyme cuts the connected parts of the hyaluronic acid chain into short pieces, and the body follows a process to process those pieces.
The first is the structure of the material.
Hyaluronic acid is a substance in the form of a long chain where two types of sugars are alternately connected.
If the chain is long, it holds a lot of water and has volume.
Filler is a material made to hold its shape by binding these chains together to increase viscosity.
The second is the action of the enzyme.
Hyaluronidase cuts specific sites where sugars are connected in this chain.
When the chain is cut short, the power to hold water decreases, and the volume also decreases.
Since filler bound with cross-linking is also made of the same chains, this enzyme acts on it as well.
The third is the processing process.
The shortened pieces are metabolized and disappear within the body.
Some people feel the change within a few hours to a day, while others see it over several days, so there are individual differences in the degree and timing.
If the remaining amount is not cleared in one session, there are cases where it is checked again after an interval.
Strengths of Gangnam filler side effect Hyalase
👉 The strengths are that the reversal path exists within the material itself, it is established as a treatment for emergency situations, and it can be used by dividing the range.
First, the reversal path is within the material.
Hyaluronic acid is a substance that exists in our body, and the enzyme that breaks it down also exists together.
So, when you are not satisfied with the shape, there is a direction you can choose other than waiting.
This is one of the reasons why you look for hyaluronic acid-based fillers when choosing filler for the first time.
Second, it is established as a treatment for emergency situations.

It is rare for filler to enter a blood vessel and block blood flow, but it is a situation that requires quick judgment.
At this time, treatment by immediately injecting a large amount of hyaluronidase is treated as a standard in academic consensus and literature.
If it is a place that handles filler, it is recommended to check if they are equipped with this enzyme.
Third, it can be used by dividing the range.
If only one side is lumpy, it is injected only in that spot, and if the amount is large overall, it is injected widely.
It is an operation that adjusts the amount and range differently depending on how much you want to reduce.
Recommended for these people
Those who can feel the injected area lumpy by hand
Those who want to tidy up only one side because the left and right shapes look different
Those who feel their expressions are awkward because too much was injected
Those who see the filler injected under the eyes shining with a blue tint
Those who want to tidy up before injecting again
Composition and Procedure
👉 The composition at Cleor Clinic Gangnam Branch is 1cc of high-purity liquid Hyalase (Hyalax), and the range and number of sessions are determined during the consultation by looking at the injected area and the remaining amount.
The procedure begins with checking what product was injected, when, where, and how much.
Whether it is hyaluronic acid-based and whether other materials are mixed in is the most necessary information first.
Next, we touch and check the lumpy area and the remaining amount to determine the range of injection.
The reason why the number of sessions is not decided in advance is because the viscosity and amount of the injected product, and the period it has been settled, differ from person to person.
After one session, we judge the next step by looking at the subsided state.
Side effects and things to know in advance
👉 Things to know are that the enzyme also acts on the hyaluronic acid of your own skin, the possibility of hypersensitivity reactions, and the scope of approved efficacy.
In the process of handling filler, the role this enzyme plays is clear.
The fact that it uses a reversible material is also a characteristic of hyaluronic acid-based fillers.

⚠️ Precautions before and after Gangnam filler side effect Hyalase procedure
❓ Frequently Asked Questions (FAQ)
Q. Can all fillers be dissolved?
A. It only acts on hyaluronic acid-based fillers.
It does not act on injectables made of fat or other materials, so a step to check what was injected is needed first.
Q. Does it return to the original skin if dissolved?
A. As the injected filler is broken down, its volume decreases.
However, it also acts on the hyaluronic acid originally in the skin, so it may look sunken for a while, and in many cases, it returns over time.
Q. How quickly can I feel the change?

A. Some people feel it within a few hours to a day, and some see it over several days.
It depends on the viscosity and amount of the injected product and the period it has been settled.
Q. Will it all dissolve at once?

A. It depends on the remaining amount and viscosity, so there are cases where it is not cleared in one session.
In that case, we check again after an interval and adjust the amount.
Q. I am worried about allergic reactions.
A. It is an ingredient for which itching, hives, and systemic reactions have been reported in rare cases.
Therefore, we check the history of hypersensitivity reactions first and proceed in a prepared state.
Q. Can I inject again immediately after dissolving?
A. If you inject new filler while the enzyme remains, that filler will also be affected.
Therefore, we schedule the re-injection after an interval and after the condition has settled.
Gangnam filler side effect Hyalase is a procedure that breaks down hyaluronic acid filler using an enzyme that cuts the connected parts of the hyaluronic acid chain into short pieces.
The domestic approved efficacy is the promotion of drug dispersion and absorption, and filler dissolution is a use beyond that scope, but it is treated as a standard for tidying up lumpy filler and emergency vascular treatment in literature and academic recommendations.
If you were concerned because the injected area felt lumpy or the left and right shapes looked different, you can consider checking the injected product first.
Cleor Clinic Gangnam Branch also operates a design filler lineup, so you can schedule the next steps after tidying up together.
I will personally check what comes first in your current state during the consultation.
If you have been constantly touching the same spot in front of the mirror, it would be good to talk about it comfortably.
※ This content is for general information purposes, and changes may vary depending on the individual.
Please determine the exact diagnosis and whether to proceed with the procedure through consultation with a specialist.
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